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Publications

Partitioning of One-Carbon Units in Folate and Methionine Metabolism Is Essential for Neural Tube Closure Kit-Yi Leung, Yun Jin Pai, Qiuying Chen, Chloe Santos, Enrica Calvani, Sonia Sudiwala, Dawn Savery, Markus Ralser, Steven S. Gross, Andrew J. Copp, Nicholas D.E. Greene Cell Reports. 2017 21(7), 1795 - 1808
Sulfate radicals enable a non-enzymatic Krebs cycle precursor Markus A. Keller, Domen Kampjut, Stuart A. Harrison & Markus Ralser Nature Ecology & Evolution . 2017 (1:0083) doi:10.1038/s41559-017-0083.
Variable repeats in the eukaryotic polyubiquitin gene ubi4 modulate proteostasis and stress survival. Rita Gemayel, Yudi Yang, Maria C. Dzialo, Jacek Kominek, Jakob Vowinckel, Veerle Saels, Leen Van Huffel, Elisa van der Zande, Markus Ralser, Jan Steensels, Karin Voordeckers and Kevin J. Verstrepen. Nature Communications ; doi:10.1038/s41467-017-00533-4 . 2017 8:397
Nonenzymatic gluconeogenesis-like formation of fructose 1,6-bisphosphate in ice. Messner CB, Driscoll PC, Piedrafita G, De Volder MFL, Ralser M. Proc Natl Acad Sci. 2017 pii: 201702274
Designing and interpreting ‘multi-omic’ experiments that may change our understanding of biology. Robert Haas, Aleksej Zelezniak, Jacopo Iacovacci, Sephan Karmad, StJohn Townsend and Markus Ralser.  Current Opinion in Systems Biology. 2017 http://dx.doi.org/10.1016/j.coisb.2017.08.009.
THADA Regulates the Organismal Balance between Energy Storage and Heat Production Moraru A, Cakan-Akdogan G, Strassburger K, Males M, Mueller S, Jabs M, Muelleder M, Frejno M, Braeckman BP, Ralser M, Teleman AA Dev Cell.. 2017 22;41(4):450
Primordial Krebs-cycle-like non-enzymatic reactions detected by mass spectrometry and nuclear magnetic resonance. Markus A. Keller, Paul C Driscoll, Christoph Messner and Markus Ralser.  Wellcome Open Res. 2017 2:52 doi: 10.12688/wellcomeopenres.12103.1
The self-inhibitory nature of metabolic networks and its alleviation through compartmentalization. Mohammad Tauqeer Alam, Viridiana Olin-Sandoval, Anna Stincone, Markus A. Keller, Aleksej Zelezniak, Ben F. Luisi and Markus Ralser.  Nature Communications . 2017 8:16018,  doi:10.1038/ncomms16018

 

Yeast Creates a Niche for Symbiotic Lactic Acid Bacteria through Nitrogen Overflow Olga Ponomarova, Natalia Gabrielli, Daniel C. Sévin, Michael Mülleder, Katharina Zirngibl, Katsiaryna Bulyha, Sergej Andrejev, Eleni Kafkia, Athanasios Typas, Uwe Sauer, Markus Ralser, Kiran Raosaheb Patil Cell Systems. 2017 https://doi.org/10.1016/j.cels.2017.09.002
The metabolic background is a global player in Saccharomyces gene expression epistasis Alam MT, Zelezniak A, Mülleder M, Shliaha P, Schwarz R, Capuano F, Vowinckel J, Radmaneshfar E, Krüger A, Calvani E, Michel S, Börno S, Christen S, Patil KR, Timmermann B, Lilley KS, Ralser M Nature Microbiology. 2016 1;1:15030