Designing and interpreting ‘multi-omic’ experiments that may change our understanding of biology.Robert Haas, Aleksej Zelezniak, Jacopo Iacovacci, Sephan Karmad, StJohn Townsend and Markus Ralser. Current Opinion in Systems Biology. 2017 http://dx.doi.org/10.1016/j.coisb.2017.08.009.
THADA Regulates the Organismal Balance between Energy Storage and Heat ProductionMoraru A, Cakan-Akdogan G, Strassburger K, Males M, Mueller S, Jabs M, Muelleder M, Frejno M, Braeckman BP, Ralser M, Teleman AA Dev Cell.. 2017 22;41(4):450
Primordial Krebs-cycle-like non-enzymatic reactions detected by mass spectrometry and nuclear magnetic resonance.Markus A. Keller, Paul C Driscoll, Christoph Messner and Markus Ralser. Wellcome Open Res. 2017 2:52 doi: 10.12688/wellcomeopenres.12103.1
The self-inhibitory nature of metabolic networks and its alleviation through compartmentalization.Mohammad Tauqeer Alam, Viridiana Olin-Sandoval, Anna Stincone, Markus A. Keller, Aleksej Zelezniak, Ben F. Luisi and Markus Ralser. Nature Communications . 2017 8:16018, doi:10.1038/ncomms16018
Partitioning of One-Carbon Units in Folate and Methionine Metabolism Is Essential for Neural Tube ClosureKit-Yi Leung, Yun Jin Pai, Qiuying Chen, Chloe Santos, Enrica Calvani, Sonia Sudiwala, Dawn Savery, Markus Ralser, Steven S. Gross, Andrew J. Copp, Nicholas D.E. Greene Cell Reports. 2017 21(7), 1795 - 1808
Sulfate radicals enable a non-enzymatic Krebs cycle precursorMarkus A. Keller, Domen Kampjut, Stuart A. Harrison & Markus Ralser Nature Ecology & Evolution . 2017 (1:0083) doi:10.1038/s41559-017-0083.
Variable repeats in the eukaryotic polyubiquitin gene ubi4 modulate proteostasis and stress survival.Rita Gemayel, Yudi Yang, Maria C. Dzialo, Jacek Kominek, Jakob Vowinckel, Veerle Saels, Leen Van Huffel, Elisa van der Zande, Markus Ralser, Jan Steensels, Karin Voordeckers and Kevin J. Verstrepen. Nature Communications ; doi:10.1038/s41467-017-00533-4 . 2017 8:397
Conditional iron and pH-dependent activity of a non-enzymatic glycolysis and pentose phosphate pathwayKeller MA, Zylstra A, Castro C, Turchyn AV, Griffin JL, Ralser M Science Advances. 2016 15;2(1):e1501235