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Publications

Unbiased Metabolomic Investigation of Alzheimer's Disease Brain Points to Dysregulation of Mitochondrial Aspartate Metabolism Paglia G, Stocchero M, Cacciatore S, Lai S, Angel P, Alam MT, Keller M, Ralser M, Astarita G Journal of Proteome Research. 2016 5;15(2):608-18
Computational tools and workflows in metabolomics: An international survey highlights the opportunity for harmonisation through Galaxy Weber RJM, Lawson TN, Salek RM, Ebbels TMD, Glen RC, Goodacre R, Griffin JL, Haug K, Koulman A, Moreno P, Ralser M, Steinbeck C, Dunn WB, Viant MR Metabolomics. 2016 13(2):12
Methionine Metabolism Alters Oxidative Stress Resistance via the Pentose Phosphate Pathway Campbell K, Vowinckel J, Keller MA, Ralser M Antioxidants & redox signaling. 2016 1;24(10):543-7
Saccharomyces cerevisiae single-copy plasmids for auxotrophy compensation, multiple marker selection, and for designing metabolically cooperating communities Mülleder M, Campbell K, Matsarskaia O, Eckerstorfer F, Ralser M. F1000Res. 2016 20;5:2351
Functional Metabolomics Describes the Yeast Biosynthetic Regulome Mülleder M, Calvani E, Alam MT, Wang RK, Eckerstorfer F, Zelezniak A, Ralser M. Cell. 2016 167(2):553-565.e12
The metabolic background is a global player in Saccharomyces gene expression epistasis Alam MT, Zelezniak A, Mülleder M, Shliaha P, Schwarz R, Capuano F, Vowinckel J, Radmaneshfar E, Krüger A, Calvani E, Michel S, Börno S, Christen S, Patil KR, Timmermann B, Lilley KS, Ralser M Nature Microbiology. 2016 1;1:15030
Analysis of Drosophila melanogaster proteome dynamics during embryonic development by a combination of label-free proteomics approaches Fabre B, Korona D, Groen A, Vowinckel J, Gatto L, Deery MJ, Ralser M, Russell S, Lilley KS Proteomics. 2016 16(15-16):2068-80
Metabolic network rewiring of propionate flux compensates vitamin B12 deficiency in C. elegans Watson E, Olin-Sandoval V, Hoy MJ, Li CH, Louisse T, Yao V, Mori A, Holdorf AD, Troyanskaya OG, Ralser M, Walhout AJ Elife. 2016 5. pii: e17670
Conditional iron and pH-dependent activity of a non-enzymatic glycolysis and pentose phosphate pathway Keller MA, Zylstra A, Castro C, Turchyn AV, Griffin JL, Ralser M Science Advances. 2016 15;2(1):e1501235
Tetrahydrobiopterin and alkylglycerol monooxygenase substantially alter the murine macrophage lipidome. Watschinger K, Keller MA, McNeill E, Alam MT, Lai S, Sailer S, Rauch V, Patel J, Hermetter A, Golderer G, Geley S, Werner-Felmayer G, Plumb RS, Astarita G, Ralser M, Channon KM, Werner ER. Proc Natl Acad Sci U S A.. 2015 112(8):2431-6