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Publications

A roadmap for interpreting (13)C metabolite labeling patterns from cells. Buescher JM, Antoniewicz MR, Boros LG, Burgess SC, Brunengraber H, Clish CB, DeBerardinis RJ, Feron O, Frezza C, Ghesquiere B, Gottlieb E, Hiller K, Jones RG, Kamphorst JJ, Kibbey RG, Kimmelman AC, Locasale JW, Lunt SY, Maddocks OD, Malloy C, Metallo CM Curr Opin Biotechnol.. 2015 34:189-201
Tetrahydrobiopterin and alkylglycerol monooxygenase substantially alter the murine macrophage lipidome. Watschinger K, Keller MA, McNeill E, Alam MT, Lai S, Sailer S, Rauch V, Patel J, Hermetter A, Golderer G, Geley S, Werner-Felmayer G, Plumb RS, Astarita G, Ralser M, Channon KM, Werner ER. Proc Natl Acad Sci U S A.. 2015 112(8):2431-6
The Impact of Non-Enzymatic Reactions and Enzyme Promiscuity on Cellular Metabolism during (Oxidative) Stress Conditions Piedrafita G, Keller MA, Ralser M Biomolecules. 2015 10;5(3):2101-22
Cytosine DNA methylation is found in Drosophila melanogaster but absent in Saccharomyces cerevisiae, Schizosaccharomyces pombe, and other yeast species. Capuano F, Mülleder M, Kok R, Blom HJ, Ralser M. Anal Chem. 2014 15;86(8):3697-702.
Inhibition of triosephosphate isomerase by phosphoenolpyruvate in the feedback-regulation of glycolysis. Grüning NM, Du D, Keller MA, Luisi BF, Ralser M. Open Biol. 2014 5;4:130232
Mitochondria in ageing: there is metabolism beyond the ROS. Breitenbach M, Rinnerthaler M, Hartl J, Stincone A, Vowinckel J, Breitenbach-Koller H, Ralser M. FEMS Yeast Res.. 2014 14(1):198-212
The RNA world and the origin of metabolic enzymes. Ralser M. Biochem Soc Trans.. 2014 42(4):985-8.
HIF1α modulates cell fate reprogramming through early glycolytic shift and upregulation of PDK1-3 and PKM2. Prigione A, Rohwer N, Hoffmann S, Mlody B, Drews K, Bukowiecki R, Blümlein K, Wanker EE, Ralser M, Cramer T, Adjaye J. Stem Cells. 2014 32(2):364-76.
A gatekeeper helix determines the substrate specificity of Sjögren-Larsson Syndrome enzyme fatty aldehyde dehydrogenase. Keller MA, Zander U, Fuchs JE, Kreutz C, Watschinger K, Mueller T, Golderer G, Liedl KR, Ralser M, Kräutler B, Werner ER, Marquez JA. Nat Commun.. 2014 22;5:4439.
Non-enzymatic glycolysis and pentose phosphate pathway-like reactions in a plausible Archean ocean Keller MA, Turchyn AV, Ralser M. Mol Syst Biol.. 2014 25;10:725