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Publications

The Impact of Non-Enzymatic Reactions and Enzyme Promiscuity on Cellular Metabolism during (Oxidative) Stress Conditions Piedrafita G, Keller MA, Ralser M Biomolecules. 2015 10;5(3):2101-22
The genomic and phenotypic diversity of Schizosaccharomyces pombe. Jeffares DC, Rallis C, Rieux A, Speed D, Převorovský M, Mourier T, Marsellach FX, Iqbal Z, Lau W, Cheng TM, Pracana R, Mülleder M, Lawson JL, Chessel A, Bala S, Hellenthal G, O'Fallon B, Keane T, Simpson JT, Bischof L, Tomiczek B, Bitton DA, Sideri T, Cod Nature Genetics. 2015 47(3):235-41
Metabolic Remodeling in Times of Stress: Who Shoots Faster than His Shadow? Dick TP, Ralser M Molecular Cell. 2015 20;59(4):519-21
Cytosine DNA methylation is found in Drosophila melanogaster but absent in Saccharomyces cerevisiae, Schizosaccharomyces pombe, and other yeast species. Capuano F, Mülleder M, Kok R, Blom HJ, Ralser M. Anal Chem. 2014 15;86(8):3697-702.
Inhibition of triosephosphate isomerase by phosphoenolpyruvate in the feedback-regulation of glycolysis. Grüning NM, Du D, Keller MA, Luisi BF, Ralser M. Open Biol. 2014 5;4:130232
Mitochondria in ageing: there is metabolism beyond the ROS. Breitenbach M, Rinnerthaler M, Hartl J, Stincone A, Vowinckel J, Breitenbach-Koller H, Ralser M. FEMS Yeast Res.. 2014 14(1):198-212
The RNA world and the origin of metabolic enzymes. Ralser M. Biochem Soc Trans.. 2014 42(4):985-8.
HIF1α modulates cell fate reprogramming through early glycolytic shift and upregulation of PDK1-3 and PKM2. Prigione A, Rohwer N, Hoffmann S, Mlody B, Drews K, Bukowiecki R, Blümlein K, Wanker EE, Ralser M, Cramer T, Adjaye J. Stem Cells. 2014 32(2):364-76.
A gatekeeper helix determines the substrate specificity of Sjögren-Larsson Syndrome enzyme fatty aldehyde dehydrogenase. Keller MA, Zander U, Fuchs JE, Kreutz C, Watschinger K, Mueller T, Golderer G, Liedl KR, Ralser M, Kräutler B, Werner ER, Marquez JA. Nat Commun.. 2014 22;5:4439.
Non-enzymatic glycolysis and pentose phosphate pathway-like reactions in a plausible Archean ocean Keller MA, Turchyn AV, Ralser M. Mol Syst Biol.. 2014 25;10:725