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Publications

The widespread role of non-enzymatic reactions in cellular metabolism. Keller MA, Piedrafita G, Ralser M. Curr Opin Biotechnol.. 2015 34:153-61.
MitoLoc: A method for the simultaneous quantification of mitochondrial network morphology and membrane potential in single cells Vowinckel J, Hartl J, Butler R, Ralser M Mitochondrion. 2015 24:77-86
Hyperpolarized [U-(2) H, U-(13) C]Glucose reports on glycolytic and pentose phosphate pathway activity in EL4 tumors and glycolytic activity in yeast cells. Timm KN, Hartl J, Keller MA, Hu DE, Kettunen MI, Rodrigues TB, Ralser M, Brindle KM. Magn Reson Med.. 2015 74(6):1543-7.
The RNA world and the origin of metabolic enzymes. Ralser M. Biochem Soc Trans.. 2014 42(4):985-8.
HIF1α modulates cell fate reprogramming through early glycolytic shift and upregulation of PDK1-3 and PKM2. Prigione A, Rohwer N, Hoffmann S, Mlody B, Drews K, Bukowiecki R, Blümlein K, Wanker EE, Ralser M, Cramer T, Adjaye J. Stem Cells. 2014 32(2):364-76.
A gatekeeper helix determines the substrate specificity of Sjögren-Larsson Syndrome enzyme fatty aldehyde dehydrogenase. Keller MA, Zander U, Fuchs JE, Kreutz C, Watschinger K, Mueller T, Golderer G, Liedl KR, Ralser M, Kräutler B, Werner ER, Marquez JA. Nat Commun.. 2014 22;5:4439.
Non-enzymatic glycolysis and pentose phosphate pathway-like reactions in a plausible Archean ocean Keller MA, Turchyn AV, Ralser M. Mol Syst Biol.. 2014 25;10:725
Cytosine DNA methylation is found in Drosophila melanogaster but absent in Saccharomyces cerevisiae, Schizosaccharomyces pombe, and other yeast species. Capuano F, Mülleder M, Kok R, Blom HJ, Ralser M. Anal Chem. 2014 15;86(8):3697-702.
Inhibition of triosephosphate isomerase by phosphoenolpyruvate in the feedback-regulation of glycolysis. Grüning NM, Du D, Keller MA, Luisi BF, Ralser M. Open Biol. 2014 5;4:130232
Mitochondria in ageing: there is metabolism beyond the ROS. Breitenbach M, Rinnerthaler M, Hartl J, Stincone A, Vowinckel J, Breitenbach-Koller H, Ralser M. FEMS Yeast Res.. 2014 14(1):198-212