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Publications

Remaining Mysteries of Molecular Biology: The Role of Polyamines in the Cell Miller-Fleming L, Olin-Sandoval V, Campbell K, Ralser M. Journal of Molecular Biology. 2015 427(21):3389-406
The return of metabolism: biochemistry and physiology of the pentose phosphate pathway. Stincone A, Prigione A, Cramer T, Wamelink MM, Campbell K, Cheung E, Olin-Sandoval V, Grüning NM, Krüger A, Tauqeer Alam M, Keller MA, Breitenbach M, Brindle KM, Rabinowitz JD, Ralser M. Biological Reviews. 2015 90(3):927-63.
A roadmap for interpreting (13)C metabolite labeling patterns from cells. Buescher JM, Antoniewicz MR, Boros LG, Burgess SC, Brunengraber H, Clish CB, DeBerardinis RJ, Feron O, Frezza C, Ghesquiere B, Gottlieb E, Hiller K, Jones RG, Kamphorst JJ, Kibbey RG, Kimmelman AC, Locasale JW, Lunt SY, Maddocks OD, Malloy C, Metallo CM Curr Opin Biotechnol.. 2015 34:189-201
HIF1α modulates cell fate reprogramming through early glycolytic shift and upregulation of PDK1-3 and PKM2. Prigione A, Rohwer N, Hoffmann S, Mlody B, Drews K, Bukowiecki R, Blümlein K, Wanker EE, Ralser M, Cramer T, Adjaye J. Stem Cells. 2014 32(2):364-76.
A gatekeeper helix determines the substrate specificity of Sjögren-Larsson Syndrome enzyme fatty aldehyde dehydrogenase. Keller MA, Zander U, Fuchs JE, Kreutz C, Watschinger K, Mueller T, Golderer G, Liedl KR, Ralser M, Kräutler B, Werner ER, Marquez JA. Nat Commun.. 2014 22;5:4439.
Non-enzymatic glycolysis and pentose phosphate pathway-like reactions in a plausible Archean ocean Keller MA, Turchyn AV, Ralser M. Mol Syst Biol.. 2014 25;10:725
Cytosine DNA methylation is found in Drosophila melanogaster but absent in Saccharomyces cerevisiae, Schizosaccharomyces pombe, and other yeast species. Capuano F, Mülleder M, Kok R, Blom HJ, Ralser M. Anal Chem. 2014 15;86(8):3697-702.
Inhibition of triosephosphate isomerase by phosphoenolpyruvate in the feedback-regulation of glycolysis. Grüning NM, Du D, Keller MA, Luisi BF, Ralser M. Open Biol. 2014 5;4:130232
Mitochondria in ageing: there is metabolism beyond the ROS. Breitenbach M, Rinnerthaler M, Hartl J, Stincone A, Vowinckel J, Breitenbach-Koller H, Ralser M. FEMS Yeast Res.. 2014 14(1):198-212
The RNA world and the origin of metabolic enzymes. Ralser M. Biochem Soc Trans.. 2014 42(4):985-8.