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Publications

The role of mitochondria in the aging processes of yeast Breitenbach M, Laun P, Dickinson JR, Klocker A, Rinnerthaler M, Dawes IW, Aung-Htut MT, Breitenbach-Koller L, Caballero A, Nyström T, Büttner S, Eisenberg T, Madeo F, Ralser M Subcell Biochem. 2012 57:55-78
Pyruvate kinase is a dosage-dependent regulator of cellular amino acid homeostasis Bluemlein K, Glückmann M, Grüning NM, Feichtinger R, Krüger A, Wamelink M, Lehrach H, Tate S, Neureiter D, Kofler B, Ralser M Oncotarget. 2012 3(11):1356-69
Pyruvate kinase triggers a metabolic feedback loop that controls redox metabolism in respiring cells Grüning NM, Rinnerthaler M, Bluemlein K, Mülleder M, Wamelink MM, Lehrach H, Jakobs C, Breitenbach M, Ralser M Cell Metab. 2011 14(3):415-27
The KRAB-containing zinc-finger transcriptional regulator ZBRK1 activates SCA2 gene transcription through direct interaction with its gene product, ataxin-2. Hallen L, Klein H, Stoschek C, Wehrmeyer S, Nonhoff U, Ralser M, Wilde J, Röhr C, Schweiger MR, Zatloukal K, Vingron M, Lehrach H, Konthur Z, Krobitsch S. Hum Mol Genet.. 2011 20(1):104-14.
No evidence for a shift in pyruvate kinase PKM1 to PKM2 expression during tumorigenesis Bluemlein K, Grüning NM, Feichtinger RG, Lehrach H, Kofler B, Ralser M Oncotarget. 2011 2(5):393-400
Human induced pluripotent stem cells harbor homoplasmic and heteroplasmic mitochondrial DNA mutations while maintaining human embryonic stem cell-like metabolic reprogramming. Prigione A, Lichtner B, Kuhl H, Struys EA, Wamelink M, Lehrach H, Ralser M, Timmermann B, Adjaye J. Stem Cells.. 2011 29(9):1338-48.
Monitoring protein expression in whole-cell extracts by targeted label- and standard-free LC-MS/MS. Bluemlein K, Ralser M. Nature Protoc.. 2011 6(6):859-69.
Cancer: Sacrifice for survival Grüning NM, Ralser M Nature. 2011 480(7376):190-1
ATM is a redox sensor linking genome stability and carbon metabolism. Krüger A, Ralser M. Science Signal.. 2011 5;4(167):pe17.
The pentose phosphate pathway is a metabolic redox sensor and regulates transcription during the antioxidant response. Krüger A, Grüning NM, Wamelink MM, Kerick M, Kirpy A, Parkhomchuk D, Bluemlein K, Schweiger MR, Soldatov A, Lehrach H, Jakobs C, Ralser M. Antioxid Redox Signal.. 2011 15;15(2):311-24.