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Publications

A new dominant peroxiredoxin allele identified by whole-genome re-sequencing of random mutagenized yeast causes oxidant-resistance and premature aging. Timmermann B, Jarolim S, Russmayer H, Kerick M, Michel S, Krüger A, Bluemlein K, Laun P, Grillari J, Lehrach H, Breitenbach M, Ralser M. Aging (Albany NY).. 2010 2(8):475-86.
The difference between rare and exceptionally rare: molecular characterization of ribose 5-phosphate isomerase deficiency. Wamelink MM, Grüning NM, Jansen EE, Bluemlein K, Lehrach H, Jakobs C, Ralser M. J Mol Med (Berl). 2010 88(9):931-9.
Regulatory crosstalk of the metabolic network Grüning NM, Lehrach H, Ralser M. Trends Biochem Sci.. 2010 35(4):220-7.
Surviving in the cold: yeast mutants with extended hibernating lifespan are oxidant sensitive. Postma L, Lehrach H, Ralser M. Aging (Albany NY).. 2009 1(11):957-60.
Interfering with glycolysis causes Sir2-dependent hyper-recombination of Saccharomyces cerevisiae plasmids Ralser M, Zeidler U, Lehrach H PLoS One. 2009 4(4):e5376
Building a new bridge between metabolism, free radicals and longevity. Ralser M, Lehrach H. Aging (Albany NY).. 2009 1(10):836-8.
Metabolic reconfiguration precedes transcriptional regulation in the antioxidant response Ralser M, Wamelink MM, Latkolik S, Jansen EE, Lehrach H, Jakobs C Nature Biotechnol. 2009 27(7):604-5
Sequencing and genotypic analysis of the triosephosphate isomerase (TPI1) locus in a large sample of long-lived Germans Ralser M, Nebel A, Kleindorp R, Krobitsch S, Lehrach H, Schreiber S, Reinhardt R, Timmermann B BMC Genet. 2008 9:38
Reductive stress on life span extension in C. elegans Ralser M, Benjamin IJ BMC Res Notes. 2008 1:19
A catabolic block does not sufficiently explain how 2-deoxy-D-glucose inhibits cell growth Ralser M, Wamelink MM, Struys EA, Joppich C, Krobitsch S, Jakobs C, Lehrach H Proc Natl Acad Sci U S A. 2008 105(46):17807-11